• The sympathetic nervous system affects the susceptibility and course of Trypanosoma cruzi infection. Roggero E, Pérez AR, Pollachini N, Villar SR, Wildmann J, Besedovsky H, Del Rey A. Brain Behav Immun. 2016 Jul 30.  https://www.ncbi.nlm.nih.gov/pubmed/27485039

 

  • An adverse immune-endocrine profile in patients with tuberculosis and type 2 diabetes. Fernández R, Díaz A, D’Attilio L, Bongiovanni B, Santucci N, Bertola D, Besedovsky H, Del Rey A, Bay ML, Bottasso O. Tuberculosis (Edinb). 2016 Dec;101:95-101. https://www.ncbi.nlm.nih.gov/pubmed/27865406

 

  • Evasion and immuno-endocrine regulation in parasite infection: Two sides of the same coin in Chagas disease? A. Morrot, S. R. Villar, F. B González, A. R. Pérez. Front. Microbiol., 23 May 2016 | http://dx.doi.org/10.3389/fmicb.2016.00704

 

  • Role of Trypanosoma cruzi Trans-sialidase on the Escape from Host Immune Surveillance. Nardy AF, Freire-de-Lima CG, Pérez AR, Morrot A. Front Microbiol. 2016 Mar 23;7:348. doi: 10.3389/fmicb.2016.00348. eCollection 2016. Review. http://www.ncbi.nlm.nih.gov/pubmed/27047464

 

  • Trypanosoma cruzi Experimental Infection Impacts on the Thymic Regulatory T Cell Compartment. González FB, Calmon-Hamaty F, Nô Seara Cordeiro S, Fernández Bussy R, Spinelli SV, D’Attilio L, Bottasso O, Savino W, Cotta-de-Almeida V, Villar SR, Pérez AR. PLoS Negl Trop Dis. 2016 Jan 8;10(1):e0004285. http://www.ncbi.nlm.nih.gov/pubmed/26745276

 

  • Trypanosoma cruzi Infection through the Oral Route Promotes a Severe Infection in Mice: New Disease Form from an Old Infection? Barreto-de-Albuquerque J, Silva-dos-Santos D, Pérez AR, Berbert LR, de Santana-van-Vliet E, Farias-de-Oliveira DA, Moreira OC, Roggero E, de Carvalho-Pinto CE, Jurberg J, Cotta-de-Almeida V, Bottasso O, Savino W, de Meis J. PLoS Negl Trop Dis. 2015 Jun 19;9(6):e0003849. http://www.ncbi.nlm.nih.gov/pubmed/26090667

 

  • Increased Frequency of CD4+ CD25+ FoxP3+ T Regulatory Cells in Pulmonary Tuberculosis Patients Undergoing Specific Treatment and Its Relationship with Their Immune-Endocrine Profile. Díaz A, Santucci N, Bongiovanni B, D’Attilio L, Massoni C, Lioi S, Radcliffe S, Dídoli G, Bottasso O, Bay ML. J Immunol Res. 2015;2015:985302. http://www.ncbi.nlm.nih.gov/pubmed/25969837

 

  • Efficacy of a Trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease. Bontempi IA, Vicco MH, Cabrera G, Villar SR, González FB, Roggero EA, Ameloot P, Callewaert N, Pérez AR, Marcipar IS. Vaccine (2015) 33(10):1274-83. http://www.ncbi.nlm.nih.gov/pubmed/25625671

 

  • Immunoendocrine dysbalance during uncontrolled T. cruzi infection is associated with the acquisition of a Th-1-like phenotype by Foxp3+ T cells. González FB, Villar SR, Fernández Bussy R, Martin GH, Pérol L, Manarin R, Spinelli SV, Pilon C, Cohen JL, Bottasso OA, Piaggio E, Pérez AR. Brain Behav Immun. 2015 Mar;45:219-32.  http://www.ncbi.nlm.nih.gov/pubmed/25483139

 

  • Molecular structures identified in serologically D negative samples of an admixed population. Trucco Boggione C, Luján Brajovich M, Tarragó M, Mattaloni S, Biondi C, Muñiz-Díaz E, Nogués N, Cotorruelo C. Transfusion 2014; 54(10): 2456-2462. http://www.ncbi.nlm.nih.gov/pubmed/24819281

 

  • Early double-negative thymocyte export in Trypanosoma cruzi infection is restricted by sphingosine receptors and associated with human Chagas disease. Lepletier A, Almeida L de, Silva Sampaio L de, Paredes B, Santos L, González FB, Beloscar J, Bottasso O, Einicker-Lamas M, Pérez AR, Savino W, Morrot A. PLoS Negl Trop Dis (2014),8(10):e3203. http://www.ncbi.nlm.nih.gov/pubmed/25330249

 

 

  • Leptin does not enhance cell-mediated immune responses following mycobacterial antigen stimulation. Santucci N, Díaz A, Bianchi E, Spinelli S, D’Attilio L, Bongiovanni B, Dídoli G, Brandan N, Nannini L, Bay ML, Bottasso O. Int J Tuberc Lung Dis. 2014 Aug;18(8):981-7. http://www.ncbi.nlm.nih.gov/pubmed/25199016

 

  • The impact of IFN-γ receptor on SLPI expression in active tuberculosis: association with disease severity.Tateosian NL, Pasquinelli V, Hernández Del Pino RE, Ambrosi N, Guerrieri D, Pedraza-Sánchez S, Santucci N, D’Attilio L, Pellegrini J, Araujo-Solis MA, Musella RM, Palmero DJ, Hernandez-Pando R, Garcia VE, Chuluyan HE. Am J Pathol. 2014 May;184(5):1268-73. doi: 10.1016/j.ajpath.2014.01.006. Epub 2014 Mar 4. http://www.ncbi.nlm.nih.gov/pubmed/24606882

 

  • Association between baseline VEGF/sVEGFR-2 and VEGF/TSP-1 ratios and response to metronomic chemotherapy using cyclophosphamide and celecoxib in patients with advanced breast cancer. Perroud HA, Rico MJ, Alasino CM, Pezzotto SM, Rozados VR, Scharovsky OG. Indian J Cancer. 2013 Apr-Jun;50(2):115-21.

 

  • Safety and therapeutic effect of metronomic chemotherapy with cyclophosphamide and celecoxib in advanced breast cancer patients. Perroud HA, Rico MJ, Alasino CM, Queralt F, Mainetti LE, Pezzotto SM, Rozados VR, Scharovsky OG. Future Oncol. 2013 Mar;9(3):451-62.

 

  • Variations of the hepatic SUV in relation to the body mass index in whole body PET-CT studies. Batallés SM, Villavicencio RL, Quaranta A, Burgos L, Trezzo S, Staffieri R, Pezzotto SM. Rev Esp Med Nucl Imagen Mol. 2013 Jan;32(1):26-32.

 

  • Levels of inflammatory cytokines, adrenal steroids, and mRNA for GRα, GRβ and 11βHSD1 in TB pleurisy.D’Attilio L, Díaz A, Santucci N, Bongiovanni B, Gardeñez W, Marchesini M, Bogué C, Dídoli G, Bottasso O, Bay ML. Tuberculosis (Edinb). 2013 Nov;93(6):635-41. doi: 10.1016/j.tube.2013.07.008. http://www.ncbi.nlm.nih.gov/pubmed/23988280

 

 

  • Altered microRNA expression levels in mononuclear cells of patients with pulmonary and pleural tuberculosis and their relation with components of the immune response.Spinelli SV, Diaz A, D’Attilio L, Marchesini MM, Bogue C, Bay ML, Bottasso OA. Mol Immunol. 2013 Mar; 53(3):265-9. http://www.ncbi.nlm.nih.gov/pubmed/22964481

 

  • Trypanosoma cruzi subverts thymic homeostasis by altering intrathymic and systemic stress-related endocrine circuitries. A Lepletier, V Frias de Carvalho, P Silva Martins, S Villar, AR Pérez, W Savino, A Morrot. PLoS Negl Trop Dis (2013);7(11):e2470. http://www.ncbi.nlm.nih.gov/pubmed/24324845

 

  • Tumor Necrosis Factor-α regulates glucocorticoid synthesis in the adrenal glands of Trypanosoma cruzi acutely-infected mice. The role of TNF-R1. Villar S, Ronco MT, Fernández Bussy R, Roggero E, Lepletier A, Manarin R, Wilson S, Pérez AR, Bottasso O. Plos One, (2013), 22;8(5):e63814. http://www.ncbi.nlm.nih.gov/pubmed/23717489

 

  • Reciprocal influences between leptin and glucocorticoids during acute Trypanosoma cruzi infection. R Manarin, SR Villar, R Fernandez Bussy, FB González, VE Deschutter, AP Bonantini, E Roggero, AR Pérez, O. Bottasso. Med Microbiol Immunol. 2013 Oct;202(5):339-52. http://www.ncbi.nlm.nih.gov/pubmed/23677171

 

  • Trans-sialidase from Trypanosoma cruzi enhances the adhesion properties and fibronectin-driven migration of thymocytes. Nardy AF, da Silva Filho JL, Pérez AR, de Meis J, Farias-de-Oliveira DA, Penha L, de Araújo Oliveira I, Dias W, Todeschini A, Freire-de-Lima CG, Bellio M, Caruso-Neves C, Pinheiro AA, Takiya CM, Bottasso O, Savino W, Morrot A. Microbes Infect. 2013 May;15(5):365-74. http://www.ncbi.nlm.nih.gov/pubmed/23481510